
Video cápsula | 15:00 min

Dra. Cristina García Ulloa
Especialista en Endocrinología
Descripción del módulo:
En este módulo se revisará una actualización sobre el riesgo cardiovascular residual, la fisiopatología de la placa vulnerable y el papel de estrategias terapéuticas dirigidas, incluyendo el uso de omega-3 en pacientes que potencialmente se puedan beneficiar de dicho tratamiento.
Objetivos de aprendizaje:
- Comprender los mecanismos del riesgo residual más allá del LDL-C.
- Identificar factores relacionados con la vulnerabilidad de la placa aterosclerótica.
- Reconocer los perfiles de pacientes que pueden beneficiarse de terapias basadas en omega-3.
Referencias:
- D’Angelo S, Motti ML, Meccariello R. ω-3 and ω-6 Polyunsaturated Fatty Acids, Obesity and Cancer. Nutrients. 2020 Sep 10;12(9):2751.
- Simopoulos AP. The importance of the omega-6/omega-3 fatty acid ratio in cardiovascular disease and other chronic diseases. Exp Biol Med (Maywood). 2008;233(6):674-688.
- Swanson D, Block R, Mousa SA. Omega-3 fatty acids EPA and DHA: health benefits throughout life. Adv Nutr. 2012;3(1):1-7.
- Jin X, Keyora. Oleic Acid (Omega-9) A Multifunctional Monounsaturated Fatty Acid in Metabolic, Cardiovascular, Neuroprotective, and Dermatological Health. 2025. Doi: 10.5281/zenodo.16901846.
- Sherratt SCR, et al. Do patients benefit from omega-3 fatty acids? Cardiovasc Res. 2024 Feb 17;119(18):2884-2901.
- Khan SU, et al. Effect of omega-3 fatty acids on cardiovascular outcomes: A systematic review and meta-analysis. EClinicalMedicine. 2021 Jul 8:38:100997.
- Dong S, et al. The effect of omega-3 Polyunsaturated Fatty Acid (PUFA) prescription preparations on the prevention of clinical cardiovascular disease: a meta-analysis of RCTs. Nutr J. 2024 Dec 6;23(1):157.
- Tutor A, et al. Omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. Prog Cardiovasc Dis. 2024 May-Jun:84:19-26.
- Shen S, et al. Omega-3 Fatty Acid Supplementation and Coronary Heart Disease Risks: A Meta-Analysis of Randomized Controlled Clinical Trials. Front Nutr. 2022 Feb 3:9:809311.
- Rodríguez D, et al. Update on Omega-3 Polyunsaturated Fatty Acids on Cardiovascular Health. Nutrients. 2022 Dec 3;14(23):5146.
- Jiang, H, et al. Omega-3 polyunsaturated fatty acid biomarkers and risk of type 2 diabetes, cardiovascular disease, cancer, and mortality. Clin Nutr. 2022 Aug;41(8):1798-1807.
- Elagizi A, et al. An Update on Omega-3 Polyunsaturated Fatty Acids and Cardiovascular Health. Nutrients. 2021 Jan 12;13(1):204.
- Watanabe Y, Tatsuno I. Prevention of Cardiovascular Events with Omega-3 Polyunsaturated Fatty Acids and the Mechanism Involved. J Atheroscler Thromb. 2020 Mar 1;27(3):183-198.